{"id":479,"date":"2009-08-26T11:49:52","date_gmt":"2009-08-26T12:49:52","guid":{"rendered":"https:\/\/turanuslu.net\/?p=479"},"modified":"2022-01-14T09:27:06","modified_gmt":"2022-01-14T09:27:06","slug":"lupus-sistemik-lupus-eritematozus-sle","status":"publish","type":"post","link":"https:\/\/turanuslu.net\/de\/lupus-sistemik-lupus-eritematozus-sle\/","title":{"rendered":"Lupus (Sistemik Lupus Eritematozus – SLE)"},"content":{"rendered":"

Lupus (Sistemik Lupus Eritematozus – SLE)<\/h2>\n

\"\"<\/p>\n

Tam ad\u0131 sistemik lupus eritematozus olan bu hastal\u0131k b\u00fcy\u00fck \u00f6l\u00e7\u00fcde 15-40 ya\u015f aras\u0131ndaki kad\u0131nlarda g\u00f6r\u00fcl\u00fcr. Lupuslular\u0131n y\u00fczde 85\u2019i kad\u0131nd\u0131r. Hastal\u0131\u011f\u0131n nedeni hen\u00fcz tam olarak anla\u015f\u0131lamam\u0131\u015ft\u0131r.
\n<\/p>\n

Lupus t\u0131pk\u0131 romatoit artrit gibi bir ba\u011f\u0131\u015f\u0131kl\u0131k sistemi bozuklu\u011fu hastal\u0131\u011f\u0131d\u0131r. Bazen ba\u015fka sebeplerle al\u0131nan ila\u00e7lar lupus belirtilerine yol a\u00e7ar. Bu ila\u00e7lar aras\u0131nda klorpromazin, hidralazin, izoniyazit, metildopa, prokainamit ve kinidin say\u0131labilir.<\/div>\n

En yayg\u0131n belirti hastalar\u0131n %90\u2019\u0131nda g\u00f6r\u00fclen eklem a\u011fr\u0131lar\u0131d\u0131r. Hastalar\u0131n bir k\u0131sm\u0131nda akci\u011fer zar\u0131nda, b\u00f6breklerde, kalpte yada beyinde iltihaplanmalar ortaya \u00e7\u0131kar ve bu bi\u00e7imiyle lupus \u00f6ld\u00fcr\u00fcc\u00fc bile olabilir. Hastal\u0131\u011f\u0131n \u015fiddeti ki\u015fiden ki\u015fiye b\u00fcy\u00fck de\u011fi\u015fkenlik g\u00f6sterir. Baz\u0131 vakalar \u00f6nemsiz, baz\u0131lar\u0131 ciddidir. Lupus en b\u00fcy\u00fck hasar\u0131 b\u00f6brekler \u00fczerinde yapar.<\/p>\n

Lupusun tedavisinde kullan\u0131lan ila\u00e7lar\u0131n \u00e7ok ciddi yan etkileri vard\u0131r. Hastal\u0131\u011f\u0131n geriletilmesinin verece\u011fi faydan\u0131n yan\u0131nda tedavide kullan\u0131lan ila\u00e7lar\u0131n yan etkileri hasta ve tedavi ekibini u\u011fra\u015ft\u0131rabilir.<\/div>\n

Belirtiler : <\/strong><\/p>\n

En yayg\u0131n belirti eklem a\u011fr\u0131s\u0131d\u0131r; ama ate\u015fe ve d\u00f6k\u00fcnt\u00fclere de s\u0131k rastlan\u0131r. Lupusa yakalananlar\u0131n yakla\u015f\u0131k yar\u0131s\u0131nda yanaklardan buruna do\u011fru kelebek bi\u00e7iminde tipik bir d\u00f6k\u00fcnt\u00fc g\u00f6r\u00fcl\u00fcr. Bu d\u00f6k\u00fcnt\u00fc g\u00fcne\u015fte kalmaya ba\u011fl\u0131 olarak ortaya \u00e7\u0131kabilir. Di\u011fer belirtiler aras\u0131nda halsizlik, kilo kayb\u0131, isteksizlik ve i\u015ftah kayb\u0131 say\u0131labilir. Hafif seyreden nispeten zarars\u0131z lupusta tedavi gerekmeyebilir ya da k\u00fc\u00e7\u00fck m\u00fcdahaleler yeterli olabilir. Sa\u00e7 d\u00f6k\u00fclmesi de s\u0131k g\u00f6r\u00fcl\u00fcr ve baz\u0131 hastalarda yara yada d\u00f6k\u00fcnt\u00fc geli\u015febilir. Kalpte, akci\u011ferde ve karn\u0131 saran zarlarda iltihaplanmalar olabilir. Kalp zar\u0131nda iltihaplanma tedavi edilmezse, kalp yetersizli\u011fi geli\u015febilir. Konjunktivit, \u0131\u015f\u0131\u011fa hassasiyet ve bulan\u0131k g\u00f6rme gibi g\u00f6z sorunlar\u0131 da ortaya \u00e7\u0131kabilir. Lupuslu baz\u0131 hastalarda kal\u0131n ba\u011f\u0131rsak sorunlar\u0131, ayr\u0131ca psikoz, havale, inme ve hal\u00fcsinasyon gibi n\u00f6rolojik sorunlarla kar\u015f\u0131la\u015f\u0131labilir. B\u00f6brek yetmezli\u011fi lupusun en \u00f6nemli komplikasyonudur.<\/div>\n

Wie wird es diagnostiziert?<\/strong><\/p>\n

Lupus te\u015fhisi koymak bazen g\u00fc\u00e7 olabilir. Doktor antin\u00fckleer antikorlar\u0131n bulunup bulunmad\u0131\u011f\u0131n\u0131 saptamak i\u00e7in bir kan tahlili isteyecektir. Bu antikorlar hemen her zaman lupusun g\u00f6stergesidir (ama lupus bulunmayan ki\u015filerin y\u00fczde 1-5\u2019inde de ayn\u0131 antikorlar saptand\u0131\u011f\u0131ndan, testin dikkatle yorumlanmas\u0131 gerekir). Yap\u0131labilecek di\u011fer tahliller aras\u0131nda hemoglobin, akyuvar ve trombosit d\u00fczeylerindeki d\u00fc\u015fmeyi belirlemeye y\u00f6nelik kan say\u0131m\u0131, anti-DNA ve anti-Sm, ayr\u0131ca idrar tahlili ve b\u00f6brek fonksiyon testleri say\u0131labilir. D\u00f6k\u00fcnt\u00fc, \u0131\u015f\u0131\u011f\u0131 duyarl\u0131l\u0131k, a\u011f\u0131zda \u00fclser ve eklem iltihab\u0131 gibi 11 \u00f6l\u00e7\u00fctten d\u00f6rd\u00fcn\u00fcn ya da fazlas\u0131n\u0131n saptand\u0131\u011f\u0131 ki\u015filer muhtemelen lupusludur.<\/div>\n

Tedavi nas\u0131ld\u0131r? <\/strong><\/p>\n

Lupus v\u00fccudun de\u011fi\u015fik sistemlerini etkileyebilir ve de\u011fi\u015fik \u015fiddetlerde ortaya \u00e7\u0131kabilir;bu sebeple tedavi de duruma g\u00f6re de\u011fi\u015fir. Nispeten hafif lupusta tedaviye pek gerek yoktur. Deri g\u00fcne\u015ften dikkatle korunmal\u0131 yada gerekti\u011finde kortikosteroit i\u00e7eren ila\u00e7lar s\u00fcr\u00fclmelidir. Dinlenme ve NSAID\u2019ler eklem a\u011fr\u0131s\u0131n\u0131 gidermek i\u00e7in yeterli olabilir. Az ya\u011fl\u0131 ve tuzlu beslenme de yararl\u0131d\u0131r. Sigara lupusun etkiledi\u011fi kan damarlar\u0131nda iltihab\u0131 art\u0131rd\u0131\u011f\u0131ndan \u00f6zellikle zararl\u0131d\u0131r. Ayr\u0131ca d\u00fczenli egzersiz yaparak eklemlerin ve kaslar\u0131n \u00e7al\u0131\u015fmas\u0131 sa\u011flanal\u0131d\u0131r.<\/div>\n
D\u00f6k\u00fcnt\u00fc yada daha ciddi eklem sorunlar\u0131 varsa, s\u0131tma ila\u00e7lar\u0131 ve kortikosteroitler gerekebilir. Lupus hayati organlar\u0131 (b\u00f6brek, kalp, akci\u011ferler, beyin) etkilenmi\u015fse, kortizon tedavisi, ba\u011f\u0131\u015f\u0131kl\u0131k sistemini bask\u0131lay\u0131c\u0131 tedavi ve hidroksiklorokin tedavisi gerekebilir. B\u00fct\u00fcn bu tedavilere ra\u011fmen lupus tedavisi zor bir hastal\u0131kt\u0131r. Bir\u00e7ok hasta da ciddi i\u00e7 organ tutulmas\u0131na ba\u011fl\u0131 olarak hayat\u0131 tehdit edici tablolar ortaya \u00e7\u0131kabilir.<\/div>","protected":false},"excerpt":{"rendered":"

Lupus (Sistemik Lupus Eritematozus – SLE) Tam ad\u0131 sistemik lupus […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[400],"tags":[432,433,434,435,436],"class_list":["post-479","post","type-post","status-publish","format-standard","hentry","category-romatizmal-hastaliklar","tag-lupus","tag-lupus-nedir","tag-lupus-tedavisi","tag-sistemik-lupus-eritematozus","tag-sle"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/turanuslu.net\/de\/wp-json\/wp\/v2\/posts\/479","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/turanuslu.net\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/turanuslu.net\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/turanuslu.net\/de\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/turanuslu.net\/de\/wp-json\/wp\/v2\/comments?post=479"}],"version-history":[{"count":2,"href":"https:\/\/turanuslu.net\/de\/wp-json\/wp\/v2\/posts\/479\/revisions"}],"predecessor-version":[{"id":10759,"href":"https:\/\/turanuslu.net\/de\/wp-json\/wp\/v2\/posts\/479\/revisions\/10759"}],"wp:attachment":[{"href":"https:\/\/turanuslu.net\/de\/wp-json\/wp\/v2\/media?parent=479"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/turanuslu.net\/de\/wp-json\/wp\/v2\/categories?post=479"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/turanuslu.net\/de\/wp-json\/wp\/v2\/tags?post=479"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}